Article
Ultrarapid hepatitis C virus clearance by daily high-dose interferon in non-responders to standard therapy.
Journal of hepatology - 1 Jun 1998
Bekkering F C, Brouwer J T, Leroux-Roels G, Van Vlierberghe H, Elewaut A, Schalm S W
Abstract excerpt
BACKGROUND/AIMS: To analyze the kinetics of the hepatitis C virus and the patterns of resistance to interferon alpha, we assessed HCV RNA levels early during retreatment with high-dose interferon in patients who did not respond to standard treatment. METHODS: Eleven non-responders to previous therapy with 3-6 MU interferon three times a week were retreated with daily 10 MU. Plasma was sampled at days 0, 1, 2, 3,...
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