Article
Mutational analysis of the herpes simplex virus triplex protein VP19C.
Journal of virology - 1 Feb 2006
Adamson Walt E, McNab David, Preston Valerie G, Rixon Frazer J
Abstract excerpt
Herpes simplex virus type 1 (HSV-1) capsids have an icosahedral structure with capsomers formed by the major capsid protein, VP5, linked in groups of three by distinctive structures called triplexes. Triplexes are heterotrimers formed by two proteins in a 1:2 stoichiometry. The single-copy protein is called VP19C, and the dimeric protein is VP23. We have carried out insertional and deletional mutagenesis on VP19C...
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