Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of charged cluster mutations on the function of herpes simplex virus type 1 UL34 protein.

Journal of virology - 1 Jul 2003

Bjerke Susan L, Cowan John M, Kerr Jelani K, Reynolds Ashley E, Baines Joel D, Roller Richard J

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) is a DNA virus that acquires an envelope by budding into the inner nuclear membrane of an infected cell. Recombinant HSV-1 lacking the U(L)34 gene cannot undergo this event. U(L)34 and U(L)31, another viral protein, colocalize in an infected cell and are necessary and sufficient to target both proteins to the inner nuclear envelope. In order to define and characterize sequences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to Fluorescent Antibody Technique, Indirect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Complementation Test

Share to Microscopy, Confocal

Share to Multigene Family

Share to Simplexvirus

Share to Vero Cells

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 12805460
DOI: 10.1128/jvi.77.13.7601-7610.2003
PMCID: PMC164785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of charged cluster mutations on the function of herpes simplex virus type 1 UL34 protein.PMID 12805460Read ↗

Herpes Simplex Virus Type 1 U <sub>L</sub> 34 Gene Product Is Required for Viral EnvelopmentSemantic proximity Read ↗

Analysis of a Charge Cluster Mutation of Herpes Simplex Virus Type 1 UL34 and Its Extragenic Suppressor Suggests a Novel Interaction between pUL34 and pUL31 That Is Necessary for Membrane Curvature around CapsidsSemantic proximity Read ↗

Effects of lamin A/C, lamin B1, and viral US3 kinase activity on viral infectivity, virion egress, and the targeting of herpes simplex virus U(L)34-encoded protein to the inner nuclear membrane.Semantic proximity Read ↗

The HSV1 Tail-Anchored Membrane Protein pUL34 Contains a Basic Motif That Supports Active Transport to the Inner Nuclear Membrane Prior to Formation of the Nuclear Egress Complex.Semantic proximity Read ↗

The herpes simplex virus type 1 glycoprotein D (gD) cytoplasmic terminus and full-length gE are not essential and do not function in a redundant manner for cytoplasmic virion envelopment and egress.Semantic proximity Read ↗

Herpes Simplex Virus 1 UL37 Protein Tyrosine Residues Conserved among All Alphaherpesviruses Are Required for Interactions with Glycoprotein K, Cytoplasmic Virion Envelopment, and Infectious Virus Production.Semantic proximity Read ↗

Role of the Arginine Cluster in the Disordered Domain of Herpes Simplex Virus 1 UL34 for the Recruitment of ESCRT-III for Viral Primary Envelopment.Semantic proximity Read ↗

Functional Domains of the Herpes Simplex Virus Type 1 Tegument Protein pUL37: The Amino Terminus is Dispensable for Virus Replication in Tissue Culture.Semantic proximity Read ↗

Herpes Simplex Virus 1 UL34 Mutants That Affect Membrane Budding Regulation and Nuclear Lamina Disruption.Semantic proximity Read ↗

A null mutation in the gene encoding the herpes simplex virus type 1 UL37 polypeptide abrogates virus maturation.Semantic proximity Read ↗

The essential protein encoded by the UL31 gene of herpes simplex virus 1 depends for its stability on the presence of UL34 protein.Semantic proximity Read ↗

A null mutation in the UL36 gene of herpes simplex virus type 1 results in accumulation of unenveloped DNA-filled capsids in the cytoplasm of infected cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.