Article
What role for DNA damage and repair in the bystander response?
Mutation research - 11 May 2006
Prise Kevin M, Folkard Melvyn, Kuosaite Virginija, Tartier Laurence, Zyuzikov Nikolai, Shao Chunlin
Abstract excerpt
The radiation-induced bystander effect challenges the accepted paradigm of direct DNA damage in response to energy deposition driving the biological consequences of radiation exposure. With the bystander response, cells which have not been directly exposed to radiation respond to their neighbours being targeted. In our own studies we have used novel targeted microbeam approaches to specifically irradiate parts of...
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