Article
Radiation-induced bystander effects and the DNA paradigm: an "out of field" perspective.
Mutation research - 11 May 2006
Mothersill Carmel, Seymour C B
Abstract excerpt
Over the past 20 years there has been increasing evidence that cells and the progeny of cells surviving a very low dose of ionizing radiation [micro-mGy] can exhibit a wide range of non-monotonic effects such as adaptive responses, low dose hypersensitivity and other delayed effects. These effects are inconsistent with the expected dose-response, when based on extrapolation of high dose data and cast doubt on the...
Topics
- Animals
- Cell Survival
- DNA
- DNA Damage
- DNA Repair
- Genomic Instability
- Humans
- Phenotype
- Radiobiology