Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon regulatory factor‐1 is prerequisite to the constitutive expression and IFN‐γ‐induced upregulation of B7‐H1 (CD274)

9 Jan 2006

Abstract excerpt

Majority of cancer cells upregulate co-inhibitory molecule B7-H1 which confers resistance to anti-tumor immunity, allowing cancers to escape from host immune surveillance. We addressed the molecular mechanism underlying the regulation of cancer-associated B7-H1 expression in response to interferon-gamma (IFN-gamma). Using promoter constructs in luciferase assay, the region between 202 and 320 bp from the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16413538
DOI: 10.1016/j.febslet.2005.12.093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon regulatory factor‐1 is prerequisite to the constitutive expression and IFN‐γ‐induced upregulation of B7‐H1 (CD274)PMID 16413538Read ↗

Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapySemantic proximity Read ↗

IL-12 Regulates B7-H1 Expression in Ovarian Cancer-associated Macrophages by Effects on NF-κB SignallingSemantic proximity Read ↗

To kill a cancer: Targeting the immune inhibitory checkpoint molecule, B7-H3Semantic proximity Read ↗

Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significanceSemantic proximity Read ↗

B7-H1 antibodies lose antitumor activity due to activation of p38 MAPK that leads to apoptosis of tumor-reactive CD8+ T cells.Semantic proximity Read ↗

MicroRNA-513 Regulates B7-H1 Translation and Is Involved in IFN-γ-Induced B7-H1 Expression in CholangiocytesSemantic proximity Read ↗

Immunoregulatory Molecule B7-H1 (CD274) Contributes to Skin CarcinogenesisSemantic proximity Read ↗

B7-H4 Expression by Nonhematopoietic Cells in the Tumor Microenvironment Promotes Antitumor ImmunitySemantic proximity Read ↗

Overexpression of B7-H3 Is Associated With Poor Prognosis in Laryngeal CancerSemantic proximity Read ↗

The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and SurvivalSemantic proximity Read ↗

The novel non‐immunological role and underlying mechanisms of B7‐H3 in tumorigenesisSemantic proximity Read ↗

Association between B7-H1 expression and bladder cancer: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.