Article
Telomere-related genome instability in cancer.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2005
De Lange T
Abstract excerpt
Genome instability is a hallmark of most human cancers. Although a mutator phenotype is not required for tumorigenesis, it can foster mutations that promote tumor progression. Indeed, several inherited cancer-prone syndromes are due to mutations in DNA repair pathways. However, sporadic tumors ar...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
