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Article

DNA damage and tumor surveillance: one trigger for two pathways.

Science's STKE : signal transduction knowledge environment - 10 Jan 2006

Höglund Petter

Abstract excerpt

Biological evolution ensures that several backup mechanisms always exist to prevent the failure of cellular processes of critical importance for life. This notion applies to processes aimed at preventing cancer development. Recent research suggests that the DNA damage response, activated in one of the earliest cellular responses to transformation, may elicit two independent tumor surveillance mechanisms. The...

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Identifiers

PMID: 16403940
DOI: 10.1126/stke.3172006pe2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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