Article
Altered light responses of single rod photoreceptors in transgenic pigs expressing P347L or P347S rhodopsin.
Molecular vision - 31 Dec 2005
Kraft Timothy W, Allen Derron, Petters Robert M, Hao Ying, Peng You-Wei, Wong Fulton
Abstract excerpt
PURPOSE: Numerous mutations of rhodopsin lead to rod cell death and ultimately to complete blindness, yet little is known about the alterations in the physiology of the light sensors containing the aberrant protein, the rod photoreceptors. METHODS: Suction pipettes were used to record the light responses from single rod photoreceptors isolated from the retinas of transgenic pigs of various ages and at progressive...
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