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Article

Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa.

Nature biotechnology - 1 Oct 1997

Petters R M, Alexander C A, Wells K D, Collins E B, Sommer J R, Blanton M R, Rojas G, Hao Y, Flowers W L, Banin E, Cideciyan A V, Jacobson S G, Wong F

Abstract excerpt

Patients with retinitis pigmentosa (RP) typically develop night blindness early in life due to loss of rod photoreceptors. The remaining cone photoreceptors are the mainstay of their vision; however, over years or decades, these cones slowly degenerate, leading to blindness. We created transgenic...

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PMID: 9335046
DOI: 10.1038/nbt1097-965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9335046-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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