Article
Animal modelling for inherited central vision loss.
The Journal of pathology - 1 Jan 2016
Kostic Corinne, Arsenijevic Yvan
Abstract excerpt
Disease-causing variants of a large number of genes trigger inherited retinal degeneration leading to photoreceptor loss. Because cones are essential for daylight and central vision such as reading, mobility, and face recognition, this review focuses on a variety of animal models for cone diseases. The pertinence of using these models to reveal genotype/phenotype correlations and to evaluate new therapeutic...
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