Multiple longevity phenotypes and the transition from health to senescence.

Abstract excerpt

Three different longevity phenotypes exist in Drosophila and other model systems, but only two are known in humans. The "missing" phenotype is the delayed onset of senescence phenotype, which can be induced by various interventions, including pharmaceuticals. The lability of the onset of senescence indicates that the mechanisms involved are plastic and can be altered. Only interventions that involve the...

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