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Article

Aging as a multifactorial disorder with two stages.

Aging - 30 Dec 2025

Gems David, Carver Alexander, Zhao Yuan

Abstract excerpt

Aging (senescence) is characterized by development of diverse senescent pathologies and diseases, leading eventually to death. The major diseases of aging, including cardiovascular disease, cancer and chronic obstructive pulmonary disease (COPD), are multifactorial disorders, resulting from complex interactions between multiple etiologies. Here we propose a general account of how different determinants of aging...

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PMID: 41474639
DOI: 10.18632/aging.206339
PMCID: PMC13147727

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