Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell stress and aging: new emphasis on multiplex resistance mechanisms.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 2009

Miller Richard A

Abstract excerpt

Work, initially in Caenorhabditis elegans and then more recently in fruit flies and mice, has suggested that anti-aging mutations extend life span by simultaneous activation of pathways that protect cells from multiple forms of injury. This "multiplex stress resistance" theory suggests a number of new avenues for investigation of the genetic and cellular controls that influence organismic longevity within and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Cellular Senescence
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Longevity

Share to Models, Animal

Share to Oxidative Stress

Share to Reactive Oxygen Species

Share to Stress, Physiological

Source

Open in PubMed Open full text

Identifiers

PMID: 19225033
DOI: 10.1093/gerona/gln072
PMCID: PMC2655020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell stress and aging: new emphasis on multiplex resistance mechanisms.PMID 19225033Read ↗

Hijacking Cellular Stress Responses to Promote LifespanSemantic proximity Read ↗

Biology of healthy aging: Biological hallmarks of stress resistance-related and unrelated to longevity in humansSemantic proximity Read ↗

Cellular stress response pathways and ageing: intricate molecular relationshipsSemantic proximity Read ↗

Stress Biology and Aging Mechanisms: Toward Understanding the Deep Connection Between Adaptation to Stress and LongevitySemantic proximity Read ↗

High throughput small molecule screening reveals NRF2-dependent and - independent pathways of cellular stress resistanceSemantic proximity Read ↗

Stress response and aging in Caenorhabditis elegans.Semantic proximity Read ↗

Worms under stress: C. elegans stress response and its relevance to complex human disease and agingSemantic proximity Read ↗

Integrating the stress response: lessons for neurodegenerative diseases from C. elegansSemantic proximity Read ↗

The cell biology of aging.Semantic proximity Read ↗

Hormesis extends the correlation between stress resistance and life span in long-lived mutants of Caenorhabditis elegans.Semantic proximity Read ↗

A unifying view of ageing and disease: the double-agent theory.Semantic proximity Read ↗

When less is more: hormesis against stress and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.