Article
Type II mixed cryoglobulinaemia as an oligo rather than a mono B-cell disorder: evidence from GeneScan and MALDI-TOF analyses.
Rheumatology (Oxford, England) - 1 Jun 2006
De Re V, De Vita S, Sansonno D, Gasparotto D, Simula M P, Tucci F A, Marzotto A, Fabris M, Gloghini A, Carbone A, Dammacco F, Boiocchi M
Abstract excerpt
OBJECTIVE: To identify and characterize rheumatoid factor (RF)-producing B-cells and cryoprecipitate immunoglobulin (Ig) M in hepatitis C virus (HCV)-positive patients. METHODS: We purified and characterized, by peptide mass fingerprinting integrated with an NCBI IgBlast data bank search, the IgM component of cryoprecipitate and analysed the VDJ pattern of bone marrow B-cells by gene scan analysis of 17...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
