Fibronectin gene polymorphisms are associated with the development of B-cell lymphoma in type II mixed cryoglobulinemia.

doi:10.1136/ard.2006.067637

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Article

Fibronectin gene polymorphisms are associated with the development of B-cell lymphoma in type II mixed cryoglobulinemia.

Annals of the rheumatic diseases - 1 Jan 2008

Fabris M, Quartuccio L, Salvin S, Pozzato G, De Re V, Mazzaro C, Ferri C, Baldini C, De Vita S

Abstract excerpt

OBJECTIVE: To analyse fibronectin (FN) gene polymorphisms in type II mixed cryoglobulinemic syndrome (MCsn), an immune-complex mediated systemic vasculitis linked to hepatitis C virus (HCV) infection and characterised by rheumatoid factor (RF) positive B-cell proliferation at high risk for the progression into non-Hodgkin's lymphoma (NHL). METHODS: Samples from 74 patients with MCsn (type II serum cryoglobulins...

Topics

Case-Control Studies
Cryoglobulinemia
Fibronectins
Gene Frequency
Genotype
Hepacivirus
Hepatitis C
Humans
Lymphoma, B-Cell
Lymphoma, Non-Hodgkin
Polymorphism, Genetic
Risk Assessment
Statistics, Nonparametric

Source

Open in PubMed

Identifiers

PMID: 17526550
DOI: 10.1136/ard.2006.067637

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