Article
A simple model of linkage disequilibrium and genetic drift in human genomic SNPs: importance of demography and SNP age.
Human heredity - 1 Jan 2005
Polanska Joanna, Kimmel Marek
Abstract excerpt
We propose a simple model of evolution at a pair of SNP loci, under mutation, genetic drift and recombination. The developed model allows to consider evolution of SNPs under different demographic scenarios. We applied it to SNP data containing polymorphisms spanning 19 gene regions. We initially...
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