Article
Genetic structure of the ancestral population of modern humans.
Journal of molecular evolution - 1 Aug 1998
Zietkiewicz E, Yotova V, Jarnik M, Korab-Laskowska M, Kidd K K, Modiano D, Scozzari R, Stoneking M, Tishkoff S, Batzer M, Labuda D
Abstract excerpt
Neutral DNA polymorphisms from an 8-kb segment of the dystrophin gene, previously ascertained in a worldwide sample (n = 250 chromosomes), were used to characterize the population ancestral to the present-day human groups. The ancestral state of each polymorphic site was determined by comparing human variants with their orthologous sites in the great apes. The "age before fixation" of the underlying mutations was...
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