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Article

MSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patens.

Nucleic acids research - 1 Jan 2006

Trouiller Bénédicte, Schaefer Didier G, Charlot Florence, Nogué Fabien

Abstract excerpt

MSH2 is a central component of the mismatch repair pathway that targets mismatches arising during DNA replication, homologous recombination (HR) and in response to genotoxic stresses. Here, we describe the function of MSH2 in the moss Physcomitrella patens, as deciphered by the analysis of loss of function mutants. Ppmsh2 mutants display pleiotropic growth and developmental defects, which reflect genomic...

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Identifiers

PMID: 16397301
DOI: 10.1093/nar/gkj423
PMCID: PMC1325206

Genes

MSH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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MSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patens.PMID 16397301Read ↗

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