Article
Regulation of plant MSH2 and MSH6 genes in the UV-B-induced DNA damage response.
Journal of experimental botany - 1 May 2011
Lario Luciana D, Ramirez-Parra Elena, Gutierrez Crisanto, Casati Paula, Spampinato Claudia P
Abstract excerpt
Deleterious effects of UV-B radiation on DNA include the formation of cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts (6-4PPs). These lesions must be repaired to maintain the integrity of DNA and provide genetic stability. Of the several repair systems involved in the recognition and removal of UV-B-induced lesions in DNA, the focus in the present study was on the mismatch...
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