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Article

Specific haplotypes of the CALPAIN-5 gene are associated with polycystic ovary syndrome.

Human reproduction (Oxford, England) - 1 Apr 2006

González A, Sáez M E, Aragón M J, Galán J J, Vettori P, Molina L, Rubio C, Real L M, Ruiz Agustín, Ramírez-Lorca R

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. The aim of the present study was to investigate the role of CALPAIN-5 (CAPN5) gene in PCOS susceptibility. METHODS: We analysed four intronic polymorphisms of the CAPN5 gene in 148 well-characterized women with PCOS and 606 unrelated controls. We performed a case-control study and an intracohort analysis of...

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Identifiers

PMID: 16396936
DOI: 10.1093/humrep/dei443

Genes

CAPN5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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