Article
Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients.
The Journal of clinical endocrinology and metabolism - 1 Nov 2003
Gonzalez Alejandro, Abril Eduardo, Roca Alfredo, Aragón Maria José, Figueroa Maria José, Velarde Pilar, Ruiz Rocío, Fayez Omar, Galán José Jorge, Herreros José Antonio, Real Luis Miguel, Ruiz Agustín
Abstract excerpt
Recently, several research groups have evaluated CAPN10 gene in polycystic ovarian syndrome (PCOS) patients and other phenotypes, including hirsutism or intermediate phenotypes of PCOS. Molecular genetic analysis of CAPN10 gene indicates that different alleles may play a role in PCOS susceptibility and could be associated with idiopathic hirsutism. However, these observations are not exempt from controversy,...
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