Article
B-cell differentiation immunophenotypes in classical Hodgkin lymphomas.
Leukemia & lymphoma - 1 Mar 2006
Bai Maria, Panoulas Vassilios, Papoudou-Bai Alexandra, Horianopoulos Nikolaos, Kitsoulis Panagiotis, Stefanaki Kalliopi, Rontogianni Dimitra, Agnantis Niki John, Kanavaros Panagiotis
Abstract excerpt
The bcl6/CD10/MUM1/CD138 B-cell differentiation immunophenotypes were analysed in 101 cases of classical Hodgkin lymphomas (cHL) aiming to elucidate their histogenesis. Three major bcl6/CD10/MUM1/CD138 immunophenotypes were distinguished on the basis of the immunohistochemical positivity of Hodgkin and Reed-Sternberg (H/RS) cells: (a) the late germinal center (GC)/early post-GC B-cell-like immunophenotype...
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