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Article

A uniform activated B-cell-like immunophenotype might explain the poor prognosis of primary central nervous system lymphomas: analysis of 83 cases.

Blood - 1 Jan 2006

Camilleri-Broët Sophie, Crinière Emmanuelle, Broët Philippe, Delwail Vincent, Mokhtari Karima, Moreau Anne, Kujas Michèle, Raphaël Martine, Iraqi Wafae, Sautès-Fridman Catherine, Colombat Philippe, Hoang-Xuan Khê, Martin Antoine

Abstract excerpt

Most primary central nervous system lymphomas (PCNSLs) in immunocompetent patients are diffuse large B-cell lymphomas (DLBCLs), characterized by poor prognosis, compared with systemic forms. A germinal center B-cell-like (GCB) origin of PCNSL was hypothesized on the basis of BCL-6 expression and ongoing mutational activity. Our goal herein was to determine, for 83 PCNSLs, the percentages of GCB and activated...

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Share to Antigens, Neoplasm
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16150948
DOI: 10.1182/blood-2005-03-1024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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