Article
Susceptibility to Buruli ulcer is associated with the SLC11A1 (NRAMP1) D543N polymorphism.
Genes and immunity - 1 Apr 2006
Stienstra Y, van der Werf T S, Oosterom E, Nolte I M, van der Graaf W T A, Etuaful S, Raghunathan P L, Whitney E A S, Ampadu E O, Asamoa K, Klutse E Y, te Meerman G J, Tappero J W, Ashford D A, van der Steege G
Abstract excerpt
Similar to other mycobacterial diseases, susceptibility to Buruli ulcer (Mycobacterium ulcerans infection) may be determined by host genetic factors. We investigated the role of SLC11A1 (NRAMP1) in Buruli ulcer because of its associations with both tuberculosis and leprosy. We enrolled 182 Buruli ulcer patients (102 with positive laboratory confirmation) and 191 healthy neighbourhood-matched controls in Ghana,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.