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Article

Aberrant methylation of p14ARF gene correlates with poor survival in osteosarcoma.

Clinical orthopaedics and related research - 1 Jan 2006

Oh Joo Han, Kim Han-Soo, Kim Hyung-Ho, Kim Woo Ho, Lee Sang Hoon

Abstract excerpt

UNLABELLED: We studied the methylation status of the CpG promoter regions of the p16 and p14 genes, mutations of four exons of the CDKN2A gene, and expressions of their corresponding proteins. Thirty-two frozen osteosarcoma tissues were used for methylation-specific polymerase chain reaction and sequence analysis. Immunohistochemical staining for p16 and p14 proteins was done. The histologic and clinical data...

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Source

Identifiers

PMID: 16394764
DOI: 10.1097/01.blo.0000188063.56091.69

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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