Article
Possible role of Abb gene in mouse resistance to EL4 metastases.
Immunogenetics - 1 Jan 1992
Egorov O S, Liu Y, Egorov I K
Abstract excerpt
"S" (survivor) mutants were produced in mice for genetic analysis of host resistance to metastatic cancers. S-mutants S-27 and S-31 resist transplantation of lymphoma EL4 of parental C57BL/6J (B6) mice while they accept parental skin grafts. Mutant S-27 also resists formation of spontaneous metas...
Topics
- Animals
- Autoradiography
- Base Sequence
- DNA
- Flow Cytometry
- Gene Expression
- Genetic Predisposition to Disease
- H-2 Antigens
- Lymphoma
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Neoplasm Metastasis