Article
Cross-regulation of JAK and Src kinases.
Growth factors (Chur, Switzerland) - 1 Mar 2006
Ingley Evan, Klinken S Peter
Abstract excerpt
Members of the Janus kinase (JAK) family, JAK1, JAK2, JAK3 and Tyk2 are intimately involved in the signalling events initiated by cytokines activating cell surface receptors. They are responsible for phosphorylating these receptors, which create docking sites for downstream molecules such as the signal transducer and activator of transcription family members. In addition, cytokine receptors associate with members...
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