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Article

Amino acid substitutions at position 38 of the DR beta polypeptide confer susceptibility to and protection from primary sclerosing cholangitis.

Hepatology (Baltimore, Md.) - 1 Aug 1992

Farrant J M, Doherty D G, Donaldson P T, Vaughan R W, Hayllar K M, Welsh K I, Eddleston A L, Williams R

Abstract excerpt

Previous studies based on serological HLA phenotyping have implicated genes in the HLA class II region in susceptibility to and protection from primary sclerosing cholangitis. In a recent report, the HLA DRw52a antigen was present in all 29 patients who had been referred for liver transplantation. In this study, HLA DRB, DQA and DQB genotypes were studied using gene amplification and sequence-specific...

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Identifiers

PMID: 1639348
DOI: 10.1002/hep.1840160217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Amino acid substitutions at position 38 of the DR beta polypeptide confer susceptibility to and protection from primary sclerosing cholangitis.PMID 1639348Read ↗

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Dual association of HLA DR2 and DR3 with primary sclerosing cholangitisSemantic proximity Read ↗

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