[Thyroglobulin (Tg) gene and familial Tg synthesis defect].

Article

[Thyroglobulin (Tg) gene and familial Tg synthesis defect].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1994

Ieiri T

Abstract excerpt

The thyroglobulin (Tg) gene is a 300-kilobase (kb) single copy gene, containing at least 42 exons, mapped in man to chromosome 8 (8q24) and codes for a glycoprotein with a molecular weight 660,000, which functions as a matrix for the thyroid hormone (T4, T3) and iodothyronine synthesis. Recent pr...

Topics

Adult
Amino Acid Sequence
Female
Goiter
Humans
Hypothyroidism
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
RNA, Messenger
Thyroglobulin
Tyrosine

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