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Article

The revised 8307 base pair coding sequence of human thyroglobulin transiently expressed in eukaryotic cells.

European journal of endocrinology - 1 May 1997

van de Graaf S A, Pauws E, de Vijlder J J, Ris-Stalpers C R

Abstract excerpt

We developed a transient transfection system for human thyroglobulin (TG) cDNA in both human thyroid cells and in COS-1 cells. Four overlapping TG cDNA fragments were amplified by reverse transcription-PCR from RNA of normal thyroid tissue. The most 5' fragment includes the natural translation initiation site and the sequence encoding the signal peptide (SP). After subcloning, the nucleotide sequence was...

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PMID: 9186272
DOI: 10.1530/eje.0.1360508

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