Article
The association of eotaxin-2 and eotaxin-3 gene polymorphisms in a Korean population with ulcerative colitis.
Experimental & molecular medicine - 31 Dec 2005
Park Young Ran, Choi Suck Chei, Lee Soo Teik, Kim Kyung Suk, Chae Soo Cheon, Chung Hun Taeg
Abstract excerpt
The eotaxin gene family (eotaxin, eotaxin-2 and eotaxin-3) have been implicated in the recruitment of eosinophils, basophiles and helper T (Th) 2 lymphocytes that is a central aspect of allergic disease. We previously suggested that Eo2+179T>C and Eo2 +275C>T of the eotaxin-2, and Eo3 +2497T>G of the eotaxin-3 were significantly associated with susceptibility to asthma. To determine whether the single nucleotide...
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