Article
Eotaxin-3 gene polymorphisms are associated with rheumatoid arthritis in a Korean population.
Human immunology - 1 Mar 2005
Chae Soo-Cheon, Park Young-Ran, Shim Seung-Cheol, Lee Il-Kwon, Chung Hun-Taeg
Abstract excerpt
The eotaxin gene family (eotaxin, eotaxin-2, and eotaxin-3) has been implicated in the recruitment of eosinophils, basophiles and Th2 lymphocytes that is a central aspect of allergic diseases. We previously suggested that Eo2+179T>C and Eo2+275C>T of the eotaxin-2, and Eo3+2497T>G of the eotaxin-3 were significantly associated with susceptibility to asthma. To precisely determine whether these single nucleotide...
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