Article
The brain-derived neurotrophic factor gene as a possible susceptibility candidate for Alzheimer's disease in a chinese population.
Dementia and geriatric cognitive disorders - 1 Jan 2006
Tsai Shih-Jen, Hong Chen-Jee, Liu Hsiu-Chih, Liu Tsung-Yun, Liou Ying-Jay
Abstract excerpt
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, may represent a candidate gene conferring susceptibility to Alzheimer's disease (AD). This is because it has an important role in neuronal survival, and a decreased central level of BDNF is observed in AD. Some previous studies, though not all, have demonstrated that BDNF C270T polymorphisms might be associated with AD...
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