Article
The C270T polymorphism of the brain-derived neurotrophic factor gene is associated with schizophrenia.
Schizophrenia research - 1 Dec 2003
Szekeres György, Juhász Anna, Rimanóczy Agnes, Kéri Szabolcs, Janka Zoltán
Abstract excerpt
We investigated a novel polymorphism of single nucleotide substitution (C270T) of the brain-derived neurotrophic factor (BDNF) gene in schizophrenia patients (n=101) and in controls (n=68). The frequency of the C/T genotype and the T allele were significantly higher in the schizophrenia patients (25.7% and 13.9%, respectively) compared with the controls (5.9% and 2.9%). There were no significant differences in...
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