Article
Regulation of cell wall synthesis by the clathrin light chain is essential for viability in Schizosaccharomyces pombe.
PloS one - 1 Jan 2013
de León Nagore, Sharifmoghadam Mohammad Reza, Hoya Marta, Curto M-Ángeles, Doncel Cristina, Valdivieso M-Henar
Abstract excerpt
The regulation of cell wall synthesis by the clathrin light chain has been addressed. Schizosaccharomyces pombe clc1Δ mutant was inviable in the absence of osmotic stabilization; when grown in sorbitol-supplemented medium clc1Δ cells grew slowly, formed aggregates, and had strong defects in morphology. Additionally, clc1Δ cells exhibited an altered cell wall composition. A mutant that allowed modulating the...
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