Article
The effects of genotype-dependent recombination, and transmission asymmetry, on linkage disequilibrium.
Genetics - 1 Mar 2006
Hellenthal Garrett, Pritchard Jonathan K, Stephens Matthew
Abstract excerpt
A recent sperm-typing study by Jeffreys and Neumann suggested that recombination rates in different individuals at the DNA2 recombination hotspot appeared to be highly dependent on their genotype at a particular A/G SNP, FG11. Specifically, individuals who carried at least one copy of the A allele at this SNP exhibited rates of crossover considerably higher than those of individuals with no copies. Further,...
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