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Article

The involvement of thioredoxin and thioredoxin binding protein-2 on cellular proliferation and aging process.

Annals of the New York Academy of Sciences - 1 Dec 2005

Yoshida Toru, Nakamura Hajime, Masutani Hiroshi, Yodoi Junji

Abstract excerpt

Recent reports on aging have revealed that many genetic loci affecting life span are closely linked to the machinery either producing or defending oxidative stress. Protective mechanisms against oxidative stress are thus important in countering the aging process. Thioredoxin (TRX) is a small thiol-mediated protein with a redox-active disulfide/dithiol within the conserved active site. TRX transgenic mice are more...

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PMID: 16387713
DOI: 10.1196/annals.1323.002

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TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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