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Article

Intrahepatic cholangiocarcinoma arising in cirrhotic liver frequently expressed p63-positive basal/stem-cell phenotype.

Pathology, research and practice - 1 Jan 2006

Nomoto Kazuhiro, Tsuneyama Koichi, Cheng Chunmei, Takahashi Hiroyuki, Hori Ryota, Murai Yoshihiro, Takano Yasuo

Abstract excerpt

In general, intrahepatic cholangiocarcinoma (ICC) is not related to liver cirrhosis. However, a few cases have been reported in which ICC was accompanied by severe liver fibrosis. Some researchers have proposed that hepatocellular and cholangiocellular (HC-CC) carcinoma, an intermediate mixed phenotype possibly arising in cirrhotic liver, might originate from hepatic precursor cells. In the liver, hepatocytes and...

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Identifiers

PMID: 16377099
DOI: 10.1016/j.prp.2005.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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