Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EpCAM+ Liver Cancer Stem-Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic Patients

18 Jan 2017

Abstract excerpt

Hepatocellular carcinoma (HCC) is believed to originate from cancer stem cells (CSCs). While epithelial cell adhesion molecule (EpCAM) is a marker of normal hepatic stem cells (HSCs), EpCAM+ cells from HCC behave like CSCs. Since HCC mostly develops on a cirrhotic background, we sought to determine whether CSC-like EpCAM+ cells exist in patients with advanced cirrhosis. Both flow cytometry and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver physiology and pathology
Share to MicroRNA in disease regulation
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28176469
DOI: 10.1002/sctm.16-0248

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EpCAM+ Liver Cancer Stem-Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic PatientsPMID 28176469Read ↗

Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell‐like propertiesSemantic proximity Read ↗

Turning Hepatic Cancer Stem Cells Inside Out – A Deeper Understanding through Multiple PerspectivesSemantic proximity Read ↗

EpCAM and α-Fetoprotein Expression Defines Novel Prognostic Subtypes of Hepatocellular CarcinomaSemantic proximity Read ↗

Characteristics of liver cancer stem cells and clinical correlations.Semantic proximity Read ↗

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cellsSemantic proximity Read ↗

Proliferating EpCAM-Positive Ductal Cells in the Inflamed Liver Give Rise to Hepatocellular Carcinoma.Semantic proximity Read ↗

Identification of microRNAs specific for epithelial cell adhesion molecule–positive tumor cells in hepatocellular carcinomaSemantic proximity Read ↗

Tumor Microenvironment Versus Cancer Stem Cells in Cholangiocarcinoma: Synergistic Effects?Semantic proximity Read ↗

A Novel Function for KLF4 in Modulating the De-differentiation of EpCAM-/CD133- nonStem Cells into EpCAM+/CD133+ Liver Cancer Stem Cells in HCC Cell Line HuH7.Semantic proximity Read ↗

Understanding the versatile roles and applications of EpCAM in cancers: from bench to bedsideSemantic proximity Read ↗

A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and epithelial-mesenchymal transitionSemantic proximity Read ↗

Liver cancer stem cell dissemination and metastasis: uncovering the role of NRCAM in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.