Article
Cytochrome P4502E1 genetic polymorphisms and risk of nasopharyngeal carcinoma: results from a case-control study conducted in Taiwan.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 1995
Hildesheim A, Chen C J, Caporaso N E, Cheng Y J, Hoover R N, Hsu M M, Levine P H, Chen I H, Chen J Y, Yang C S
Abstract excerpt
CYP2E1 is responsible for the metabolic activation of nitrosamines believed to be involved in the pathogenesis of various tumors. Nasopharyngeal carcinoma (NPC) is a tumor thought to be linked to nitrosamine exposure. To investigate the possible role of CYP2E1 genetic polymorphisms in the etiolog...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Base Sequence
- Case-Control Studies
- Confidence Intervals
- Cytochrome P-450 CYP2E1
- Cytochrome P-450 Enzyme System
- Female
- Gene Expression
- Genotype
- Humans