Article
Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation.
Arthritis and rheumatism - 1 Dec 2010
Minogue Ben M, Richardson Stephen M, Zeef Leo A H, Freemont Anthony J, Hoyland Judith A
Abstract excerpt
OBJECTIVE: Development of stem cell therapies for regenerating the nucleus pulposus (NP) are hindered by the lack of specific markers by which to distinguish NP cells from articular chondrocytes (ACs). The purpose of this study was to define the phenotype profile of human NP cells using gene expression profiling and to assess whether the identified markers could distinguish mesenchymal stem cell (MSC)...
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