Article
Identification of phenotypic discriminating markers for intervertebral disc cells and articular chondrocytes.
Rheumatology (Oxford, England) - 1 Nov 2009
Clouet Johann, Grimandi Gaël, Pot-Vaucel Marianne, Masson Martial, Fellah Hakim B, Guigand Lydie, Cherel Yan, Bord Eric, Rannou François, Weiss Pierre, Guicheux Jérôme, Vinatier Claire
Abstract excerpt
OBJECTIVE: The present study was conducted to improve our knowledge of intervertebral disc (IVD) cell biology by comparing the phenotype of nucleus pulposus (NP) and annulus fibrosus (AF) cells with that of articular chondrocytes (ACs). METHODS: Rabbit cells from NP and AF were isolated and their phenotype was compared with that of AC by real-time PCR analysis of type I (COL1A1), II (COL2A1) and V (COL5A1)...
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