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Article

Alterations of the penicillin-binding proteins and murM alleles of clinical Streptococcus pneumoniae isolates with high-level resistance to amoxicillin in Spain.

The Journal of antimicrobial chemotherapy - 1 Feb 2006

Cafini Fabio, del Campo Rosa, Alou Luis, Sevillano David, Morosini María Isabel, Baquero Fernando, Prieto José

Abstract excerpt

AIMS: The aim of this study was to analyse the nucleotide sequences of regions encoding the penicillin-binding domains of pbp1A, pbp2B and pbp2X genes and murM alleles from 14 selected amoxicillin-resistant Streptococcus pneumoniae isolates (MICs 8-16 mg/L) obtained in Spain. METHODS: PFGE and dideoxynucleotide chain termination sequencing were used. RESULTS: Analysis of PFGE profiles showed that the...

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PMID: 16368701
DOI: 10.1093/jac/dki442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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