Article
Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns.
International journal of antimicrobial agents - 1 Aug 2003
Ohsaki Yoshinobu, Tachibana Mineji, Nakanishi Kyoko, Nakao Shoko, Saito Kumiko, Toyoshima Eri, Sato Maki, Takahashi Toru, Osanai Shinobu, Itoh Yoshihisa, Kikuchi Kenjiro
Abstract excerpt
Penicillin binding protein (pbp) gene alterations of 328 clinical isolates of Streptococcus pneumoniae were examined for a correlation with their antibiotic-resistance. The frequency of penicillin G (PEN-G) resistance was determined to clarify susceptibility to several antibiotics, namely PEN-G, ampicillin, sulbactam/ampicillin, cefozopram, panipenem (PAPM), clarithromycin (CLR), azithromycin (AZM) and...
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