Article
Molecular characteristics of penicillin-binding protein genes of penicillin-nonsusceptible Streptococcus pneumoniae isolated in the Netherlands.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2001
Overweg K, Bogaert D, Sluijter M, de Groot R, Hermans P W
Abstract excerpt
Recently, a nation-wide molecular epidemiologic survey of penicillin-nonsusceptible Streptococcus pneumoniae has been performed in the Netherlands. In the current study, we analyzed the genes pbp1a, pbp2b, and pbp2x from these clinical isolates at the molecular level, and identified the genetic composition of the penicillin-binding domains. The pneumococcal strains were selected on the basis of differences in...
Topics
- Aminoacyltransferases
- Bacterial Proteins
- Carrier Proteins
- Culture Media
- DNA Primers
- Genotype
- Hexosyltransferases
- Humans
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Muramoylpentapeptide Carboxypeptidase
- Netherlands
- Penicillin Resistance