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Article

Clinicopathological Parameters and Immunohistochemical Profiles in Correlation with MRI Characteristics in Glioblastomas.

International journal of molecular sciences - 4 Dec 2024

Sipos Tamás-Csaba, Attila Kövecsi, Kocsis Lóránd, Bălașa Adrian, Chinezu Rareș, Baróti Beáta Ágota, Pap Zsuzsánna

Abstract excerpt

Glioblastoma is considered the most aggressive tumor of the central nervous system. The tumor microenvironment includes several components, such as endothelial cells, immune cells, and extracellular matrix components like matrix metalloproteinase-9 (MMP-9), which facilitates the proliferation of endothelial cells with pro-angiogenic roles. The MRI characteristics of glioblastomas can contribute to determining the...

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Identifiers

PMID: 39684754
DOI: 10.3390/ijms252313043
PMCID: PMC11642654

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