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Article

Analysis of sequential hepatitis A virus strains reveals coexistence of distinct viral subpopulations.

The Journal of general virology - 1 Jan 2006

Costa-Mattioli Mauro, Domingo Esteban, Cristina Juan

Abstract excerpt

Hepatitis A virus (HAV) is a hepatotropic member of the family Picornaviridae. Despite a remarkable antigenic stability, recent results have shown that HAV exists in vivo and in cell culture as distributions of genetically related, non-identical variants, referred to as quasispecies. To gain insight into HAV evolution over time in a specific geographical region, genotype I consensus sequences from strains...

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PMID: 16361423
DOI: 10.1099/vir.0.81286-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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