Article
Genetic diversity of hepatitis A virus in China: VP3-VP1-2A genes and evidence of quasispecies distribution in the isolates.
PloS one - 1 Jan 2013
Wang Hao, Zheng Huihui, Cao Jingyuan, Zhou Wenting, Yi Yao, Jia Zhiyuan, Bi Shengli
Abstract excerpt
Hepatitis A virus (HAV) is the most common cause of infectious hepatitis throughout the world, spread largely by the fecal-oral route. To characterize the genetic diversity of the virus circulating in China where HAV in endemic, we selected the outbreak cases with identical sequences in VP1-2A junction region and compiled a panel of 42 isolates. The VP3-VP1-2A regions of the HAV capsid-coding genes were further...
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