Article
EGF-Induced Cell Migration Is Mediated by ERK and PI3K/AKT Pathways in Cultured Human Lens Epithelial Cells
1 Apr 2006
Abstract excerpt
Cataract is considered as the most common cause of blindness, which is curable only by surgery. Postsurgery, however, many patients gradually develop the complication of posterior capsule opacification (PCO) or secondary cataract, arising from stimulated cell proliferation and cell migration within the lens capsule. The migration of human lens epithelial cells (HLECs) plays crucial roles in the remodeling of lens...
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